Saturday, February 16, 2008
Breast giant fibroadenoma and lobulated cystic breast sarcoma relations?
Breast giant fibroadenoma and lobulated cystic tissue sarcoma structure is very similar, therefore, the previous literature often confuse the two, said breast giant fibroadenoma "benign lobulated cystic sarcoma," while the lobulated cystic sarcoma called "vicious lobulated cystic sarcoma." Shanghai Medical University Cancer Hospital oncology clinical and histological study of such tumors are benign morphologic features are known as giant fibroadenoma, and lobulated cystic sarcoma should be those mesenchymal cells malignant tumor performance . Because of the structure of the histological similarity, the general view, lobulated cystic sarcoma from the breast fibroadenoma, or giant fibroadenoma, but some scholars believe that lobulated cystic sarcoma is not transformed from the fibroadenoma, but from the very beginning which is lobulated cystic sarcoma. Breast giant fibroadenoma and the general fibroadenoma is very similar to the clinical process, and lobulated cystic sarcoma have a special clinical performance. Cystosarcoma phyllodes breast sarcoma at the age of onset larger, with an average of 40 8 to 49 years old, long history, but often short-term rapid growth of tumor history. Masses are typically larger, and often more than 5 cm, involving milk. Masses were round or irregular in shape, sustained lobulated, texture is tough and flexible, and sometimes there can be sexy capsule. Mass clear boundary, and the surrounding skin and breast tissue no adhesion, activities. Local skin temperature normal or slightly higher, with orange peel and Rutouaoxian levy. Huge mass, low local skin, subcutaneous visible expansion of superficial vein, and in Huipo and outflow purulent secretions. This shows that some patients with axillary lymphadenopathy. Lobulated cystic breast sarcoma thoroughly after resection, the general prognosis is good, even after local recurrence, as long as further extended resection not affect the prognosis, and the event of a transfer of blood will affect the prognosis. In the performance of the two organizations, their constituents are benign epithelial and mesenchymal some of the fiber hyperplasia. Giant fibroadenoma with benign cytology characteristics, and the small rules, atypia not obvious, and lobulated cystic stromal sarcoma of the components has a different degree of atypia and mitotic rate.
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