Saturday, February 16, 2008

Breast intraductal papilloma what disease and the need for differential diagnosis?

Intraductal papilloma of the breast to breast and intraductal papillary carcinoma and breast ductal expansion phase syndrome identification. (1) intraductal papilloma of the breast and breast intraductal papillary carcinoma: the two can be seen spontaneous, painless bloody nipple discharge; are palpable and areola of the mass, and the press can be mass Since the duct openings overflow bloody liquid. Because of the clinical manifestations and morphological characteristics are very similar, so both the differential diagnosis very difficult. Generally believed that breast intraductal papilloma the discharge can be bloody, bloody or slurry can also serous, and papillary carcinoma of the discharge, while bloody The most common, and more unilateral single hole. Papilloma mass located in the areola, soft texture, and the general mass of not more than 1 cm, no ipsilateral axillary lymph node swelling, and papillary carcinoma tumor located in the area outside the areola, the hard texture of the surface not smooth, activities of the poor, vulnerable and skin adhesion, the general mass larger than 1 cm, that the ipsilateral axillary lymph node enlargement. Galactography show catheter sudden interruption stump was smooth cup-shaped mouth, proximal catheter shows a clear expansion, sometimes round or oval filling defect, catheter soft, light the whole, most of intraductal papilloma; if stump vary, proximal catheter mild expansion, distortions, are disordered, filling defect or complete obstruction, catheter loss of flexibility and become rigid, then the number of intraductal carcinoma. Discharge smear cytology papillary carcinoma cells can be found. Eventually diagnosed while pathological diagnosis prevail, and paraffin sections should be done to avoid the limitations of frozen sections cause false positive or false negative results. (2) intraductal papilloma of the breast and breast dilatation syndrome: intraductal papilloma and dilatation of the discharge phase syndrome can nipple discharge as the main symptoms, but dilatation congenital syndrome accompanied nipple Depression, bilateral discharge more porous, water samples showed character can be, like milk, serous like Nongxue or bloody; papilloma syndrome and dilatation of the mass could be seen under the areola mass, but after the masses often larger than the former, and the mass irregular in shape, texture hard and tough, with skin adhesive, and often swelling in pain, can occur late Huipo and discharging. Dilatation syndrome can also be found in the ipsilateral axillary lymph node swelling, tenderness. Galactography show catheter suddenly interrupted, the filling defect in the rules, most of papilloma; if expansion was significantly larger catheter, catheter uneven thickness, loss of the normal rules of dendritic appearance, the most comprehensive dilatation levy. When necessary, viable mass-needle aspiration cytology or live pathological examination.

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