Tuesday, February 19, 2008

Causes of sexual dysfunction

  (a) age and ED     increase with age, erectile function in a series of changes, with the exception of sex fell from the penis less sensitive to the length of erection, erection relies more heavily on the physical stimulation, psychological responses to weaken, and erection hardness decreased, with orgasm and ejaculation change, the intensity of sexual pleasure weakened the strength of ejaculation and semen volume decreased, the number of sexual activity also decreased.       final All men have gone through these changes, but change at different rates, their own judgement whether there ED, each of the different standards, but significant portion of older men, there are indeed ED, and except for the age factor, and found no other reasons. Many pathophysiology and age-related factors, such as 45-year-old after the plasma (bioavailable) testosterone levels with increased levels of SHBG and is gradually declining.     In addition, since the fall of pituitary LH secretion of prolactin and increase in serum total testosterone levels decline. There is no doubt that some of the elderly is due to vascular lesions induced ED. The penis, many pathophysiological process do seem related and chronic vascular disease, or secondary to chronic vascular disease. Physiological factors in these synergies, the psychological factors can add any type of ED, such as: ignore the elderly need more time to arouse their sexuality to increase its activities in the anxiety, and can lead to a vicious circle, the end, the complete loss of erectile function.     When an elderly male sexual function gradually found its decline, he may not shy flexor in the treatment. However, as the elderly population increases and women's hormone replacement therapy, eager to maintain its elderly male sexual function, particularly as a treatment for the improvement of innovation and efficacy, more and more people are determined for the treatment of ED.     (2) Diabetes     about 50 per cent of ED patients with diabetes mellitus, diabetes majority of the people in the development process of the formation of ED, a small number of people there ED earlier. Although some data indicate that diet to control diabetes in people less ED, but most of the reported incidence of ED in oral hypoglycemic agents and insulin injections there is no difference between the groups, suggesting that ED may occur and the degree of blood glucose control .     diabetic ED and the pathophysiological process of a variety of factors, diabetic neuropathy and arterial lesions induced ED has been gaining a clear understanding of the role of (Table 10), diabetic autonomic neuropathy caused the ED, and it can accelerate atherosclerosis occurred, and its role outlined in the table. The traditional view that diabetes caused gonadal dysfunction to some extent and cause endocrine disruption, the ED attributed this. But now people focus on the penis, the role of vascular endothelial cells and smooth muscle control, and more and more evidence that diabetes led to systemic endothelial cells and smooth muscle dysfunction, the penis, resulting ED.     (c) of chronic renal failure with ED     chronic renal failure and dialysis treatment of patients with ED rate was 50-80 per cent, and many pathophysiological processes involved in the occurrence of ED, including hyperprolactinemia, and gonadal function of the lower secondary cycle in the endotoxin-induced smooth muscle dysfunction, neurological disease and arteriosclerosis, the other, resulting in renal failure diseases such as diabetes and complications of renal failure (such as hypertension) treatment, is also involved in the occurrence of ED. If the cavernous irreversible lesions occurred prior to renal transplantation, and often can improve erectile function in patients with sick to their former level.     (d) the erectile tissues of abnormal cavernous erectile dysfunction causes outside the cavernous have been discussed in detail above, but unencumbered corpus cavernosum smooth muscle cells or normal cells to change the complex situation, at least partly explain the cause of erectile dysfunction. Erectile dysfunction can be seen as multi-factor disease, but each may be a potential mechanism and other mechanisms of mutual dependence. Recent research that erectile dysfunction may cavernous there are three causes: ① substantive change ② neuropathy; ③ corpus cavernosum smooth muscle tension changes, including the relaxation of barriers to enhance or contraction.

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