Tuesday, February 19, 2008

Choriocarcinoma

Etiology: Choriocarcinoma, or choriocarcinoma, is a highly malignant tumor. And the vast majority of pregnancy-related choriocarcinoma were secondary to hydatidiform mole, normal after childbirth or abortion. There are reports that can occur directly from the Yunkun, and even a few from teratoma contained eggs nourishment of the ingredients. Occurred in tubal pregnancy or abdominal pregnancy rarely see. Clinical manifestations: A different history of pregnancy or choriocarcinoma normal from abnormal pregnancy, but at least 50 per cent obviously mole history. According to Beijing 414 cases of choriocarcinoma have a clear history of previous pregnancies, directly from the previous pregnancy, as hydatidiform mole of 56.8% for the previous pregnancy or full-term abortion, but the history of hydatidiform mole, the total comes from hydatidiform mole , choriocarcinoma from the mole, was 69.1%, the villi hydatidiform mole hidden in the body has no depositors to suspect. Trophoblast cells malignant mole rate is higher than pregnancy cells. According to Union Hospital reported that the abortion had hydatidiform mole in the history of the future development of choriocarcinoma, 16%; term pregnancy have a history of hydatidiform mole 35 per cent. This shows that the history of a mole potentially dangerous. B, vaginal bleeding after childbirth or abortion, especially in the post-abortion hydatidiform mole with irregular vaginal bleeding. Bloodshed can be immediately after childbirth or abortion, but also between the time lag. Even in a very small number of bleeding during pregnancy. Output can that can be less. Post-natal or post-abortion uterine involution can not be on schedule, and even in some cases it has increased. Some nodules vaginal bleeding from the vagina. Vaginal bleeding for choriocarcinoma earliest, the most common symptoms. But also whether individual bleeding symptoms. C, abdominal mass course of a long and significant increases uterus, or in the metastatic form within the broad ligament hematoma, there will be abdominal mass. Individual in the primary ovarian or fallopian tubes, also, there may be lower abdominal mass. D, abdominal pain because of the erosion of uterine cancer or uterine wall caused by the accumulation of blood clots. Acute abdominal pain may be due to uterine choriocarcinoma wear ulcer or abdominal hemorrhage caused by liver metastases. E, metastasis 1, common to lung metastasis, patients can have symptoms Caledonia blood, but also because of other disease treatment by chest X-ray or pulmonary X-ray film and identified. 2, vagina, vulva metastatic nodules in the gynaecological examinations, investigations see very easily, round or long in shape, to a few centimetres in diameter, the lower anterior vaginal more, and sometimes rupture bleeding, a few resulted in a large number vaginal flow. 3, or brain metastasis occurred. For brain metastasis or penetrating spider membrane formation subarachnoid hemorrhage. Headache patients with space-occupying lesions and, if a limb paralysis. Bleeding for a long time, appeared unconscious, or even killed instantly. Some patients died suddenly in a coma, brain autopsy confirmed choriocarcinoma cell carcinoma, and no uterus original lesion. 4, retinal transfer, and some are governed by bilateral retinal violations. But did not mention whether the vision fully restored. F, abdomen, a transfer lesions, liver metastases: liver pain, hepatomegaly, can be misdiagnosed as cholecystitis or amebic liver abscess. 2, jaundice: the outcome of liver metastasis. 3, abdominal hemorrhage: acute abdominal pain. Bleeding can come from the liver, spleen, uterus or fallopian tubes, such as the rupture metastasis. Sudden massive bleeding often patients in a shock, or even death. 4, intestinal bleeding: for the performance of upper gastrointestinal bleeding is black, ink would like metastases compared to the past from the fresh anal bleeding. Accompanied abdominal pain, anemia. G, amenorrhea not only in individual cases of choriocarcinoma uterine bleeding, but there are symptoms of amenorrhea.

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