Sunday, February 17, 2008

The clinical stage of prostate cancer

1) A period of the disease: A period lesions completely confined to the prostate, Volume is very small, no symptoms, only occasionally when in search of discovery. Disseminated no local or distant, difficult to detect clinically. Only through autopsy pathology, or benign prostatic hyperplasia biopsy specimens removed specimens to the inspection diagnosis. Lesions limitations and cell differentiation good, growth is slow and can not be touched DRE examination nodules, clinical without metastasis disease, prostate cancer about this period of nine percent. Prospective and retrospective studies show that A period of general good prognosis, in the majority of patients do not progress to clinical lifetime cancer or hidden cancer.
(2) B lesions: B lesions confined to the prostate capsule, larger tumor, but not yet a breakthrough prostatic cysts, mostly in the digital rectal examination of the prostate found a single nodule, no distant metastasis signs. Through prostate biopsy histologic examination diagnosed. B for the period in the development of prostate cancer than the short-term period, it found clinical cases less, or about prostate cancer around 11%.
(3) stage C disease: lesions beyond the prostate capsule, can be violations of the neighboring seminal vesicle, bladder neck, and other nearby tissues and organs, but no evidence of distant metastasis. C prostate cancer treatment is not about 60% of patients within five years her illness became more serious, the 10-year half of a shift, 75 percent died of prostate cancer. This period of about prostate cancer 44%.
(4) D illness: beyond the prostate lesions, and distant metastases, the remote bones, and even lung, liver and adrenal metastasis can occur. D poor prognosis of patients, the majority after three years in the diagnosis of carcinoma died of distant metastasis. This period of about 36 percent.
Clearly the prostate cancer staging helps to understand the scope of diseases, prognosis and development of treatment programs. For A and B patients, because basically confined lesions in the prostate, can strive for the early radical prostatectomy; on the C, D view has been and distant metastasis of prostate, patients can only do palliative resection of the prostate, coupled with endocrine therapy and radiotherapy and chemotherapy treatment.

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