Differential diagnosis of systemic lupus erythematosus

Should this disease and other connective tissue diseases, Bacterial or viral infection of the disease, cell hyperplasia X, reticular endothelial cells increased malignant disease, thrombocytopenia disease, hemolytic anemia, various types of kidney disease, hepatitis, myocardial - pericarditis, diseases of the nervous system identification. In particular category with lupus syndrome, neonatal lupus erythematosus syndrome differentiation. Category lupus syndrome, the most common drug-induced systemic lupus erythematosus. SLE similar to the syndrome that some symptoms, signs, and laboratory test results, and sometimes. Some of the conditions which would identify the following: history of taking such drugs, not obvious gender differences, the clinical symptoms light, visceral involvement, kidney disease, butterfly erythema, mouth ulcers, hair loss, and the WBC, thrombocytopenia, hypocomplementemia are rare , anti - Sm antibodies and anti-n-DNA (FARR) antibody negative. The most important feature is after stopping clinical symptoms and laboratory signs disappeared, when another drug rehabilitation now. Sometimes ANA longer exist, the general prognosis is good. Neonatal lupus erythematosus syndrome of the disease is seen at six months following baby. In the majority of children with mothers suffering from SLE or other connective tissue diseases, in the RO serum antigen (Sjogren's syndrome A antigen) and La antigen (Sjogren's syndrome B antigen). After the children have symptoms of Health, mainly for congenital block, lupus-like dermatitis, and self-hemolytic anemia, and in vivo RO La antigen positive. In addition, accompanied congenital heart disease, all kinds of defects and endocardial fibroelastosis, WBC and platelet reduction. A typical example of the lesions for pleadings and annular erythema, is seen at the Department of exposure, that is, head, neck and eyelids, seems to discoid erythema. The disease is self-limited disease, abnormal blood more than six weeks improved, the skin lesions can be six months disappear. In addition to children with heart disease, the general prognosis is good. It is reported puberty can be a SLE, the reason is unclear.