Sunday, February 17, 2008

Endometrial cancer diagnosis and treatment

Endometrial cancer also known as the Palace of cancer. The incidence of malignant tumors of the female genital section three, in recent years, there is an upward trend. 80% occurred in 50 women over the age of 80% to 90% of adenocarcinoma. Exact cause unknown, its occurrence and stimulate long-term estrogen-related. [Diagnosis] 1, history (1) infertility, obesity, hypertension, diabetes as high risk factors. (2) whether reactive blood type ovulation, polycystic ovary syndrome, such as endometrial hyperplasia history. (3) menopause delay. (4) a longer time to use estrogen formulations. 2, symptoms (1) irregular bleeding, especially after menopause. (2) increased vaginal discharge fluid, water samples were yellow or bloody. Late Commissioner of infection, blood samples showed dense liquid discharge. (3) advanced carcinoid tumor infiltration if oppression surrounding tissue or nerve can lumbosacral pain in the lower abdomen and to the lower limb and foot radiation. If cervical cancer plug the tubes, leading to intrauterine empyema, spasm-like pain in the lower abdomen. 3, signs early gynecological examinations no obvious abnormalities. Late uterus increased, softened, fixed,a block of nodular, occasionally cervical cancer since I prolapse. 4, auxiliary inspection (1) diagnostic curettage to use small scratch engines Central scraping neck tubes, re-enter the uterine cavity were Palace, the Palace at the bottom endometrium. With signs of the times should beware of possible uterine perforation. Especially when the scraps bean dregs tissue with a high degree of suspicion for endometrial cancer, should immediately stop operation. Markings were made of scraps sent pathological examination. (2) hysteroscopy attending scraping negative, and a history of cancer suspicious when feasible hysteroscopy, endometrial open. If tumors can be directly observed its location, size, growth patterns, based delivery and pathological examination. [Treatment] 1, the preferred method for surgical treatment. For patients with Stage I fascia, hysterectomy and bilateral resection of the annex, the secondary should be in addition to extensive section of hysterectomy and pelvic lymphadenectomy for. 2, surgery and radiation treatment in patients with Stage I or ascites cells found in a layer of muscle invasive cancer, lymph node metastasis, plus postoperative irradiation in vitro. Part II or III patients with preoperative radiotherapy plus or intracavitary irradiation, the end of radiotherapy after 1 to 2 weeks to conduct surgery. 3, radiotherapy for the elderly infirm and can not have serious medical complications resistance surgery, and III should not be for more than surgery, radiation therapy may include cavity and in vitro irradiation. 4, in the treatment of young patients with early reservations requested reproductive function, not surgery or advanced cancer patients with recurrent cancer, can be a large dose of synthetic progesterone treatment. If Medroxyprogesterone 400 mg intramuscular injection per week 2 to 3 times; have acid progesterone 500 mh, intramuscular injection, weekly 2-3 inferior. At least 12 weeks to evaluate efficacy. 5, the anti-estrogen drug tamoxifen, and indications of the same progesterone treatment, the general dose of 20 to 40 mg / d, oral, long-term use or application of the treatment. 6, anti-cancer chemotherapy for advanced or not surgery after radiotherapy treatment and relapse cases, available 5 - fluorouracil (5 - Fu), and cyclophosphamide (CTX), mitomycin C (MMC), Azerbaijan mycophenolate - (BDR), cisplatin (DDP), combined with chemotherapy and have a certain effect. 7, anti-cancer traditional Chinese medicine treatment can be used as one of the measures to comprehensive treatment, apply to some not suitable for surgery and radiotherapy and chemotherapy or relapse after surgery patients. Hebei Tumor Hospital Fu Shan Chinese high-tech achievements developed using the cellular and molecular regulation of tumor suppressor medicine, "Fu Shan God" series of agents (capsules, oral liquid, etc.) and tumor suppressor injections, breaking the "poisonous cancer, killing cancer, anti - cancer, "" traditional set thinking, "There is no toxic drug itself, not the cancer have a direct positive stimulus, it is cell gene therapy in clinical application. Its principle is the grams of cancer: carcinoid tumor angiogenesis inhibiting the formation of networks, blocking nutrient supply to the cancer cells, cancer cells metabolic cut off channels, causing cancer are not sources of nutrients gradually withered, the waste can not be discharged gradually degeneration and necrosis, and do not harm normal cells. In enhancing the body's own immune function, and promote the body's anticancer immune monitoring system regeneration, the activation of various types of cancer cells kill At the same time, cell cycle regulation and cell molecular dynamic engine, lost control of the cancer cell cycle back to normal rhythm, so that cancer cells reversed. The drug with chemotherapy and radiotherapy, can significantly reduce the release of the toxic side effects of chemotherapy, raising the number of white blood cell. Even has lost surgery, radiotherapy and chemotherapy in patients with advanced opportunities, but also control the transfer, less cancer pain, improve Syndrome, improve quality of life and prolong survival time with cancer.

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