Endometrial cancer diagnosis

Endometrial cancer diagnosis by the above steps, the general is not difficult, but sometimes can be confused with other diseases, as well as delay in diagnosis. With the following identification: First, bleeding after menopause should first alert whether the cancer, although with the progress of postmenopausal bleeding in the proportion of cancer has been greatly decreased. If Knitis such reports, the 40 postmenopausal vaginal bleeding or malignant diseases in the 60 ~ 80%, 70 to 25 years-long ~ 40%, dropped to 80 in the 6 to 7 per cent. China, and others-should be reported, the 1960s accounted for 76.2% of malignant disease, endometrial cancer accounted for 12.9% .80 malignant disease in the late Huang Hefeng such reports, accounting for 22.7% of malignant disease, and endometrial cancer accounted for 45.5% of malignant cases , cervical cancer accounts for 43.6 per cent. Ying such reports and malignant diseases accounted for 24.9% (73.3% of benign), ranking the first postmenopausal bleeding 2. From the duration of menopause, menopause five years of 14%, 5 ~ 15 postmenopausal women who accounted for 68.3 percent. Thus, in malignant tumors with the progress of endometrial cancer are on the rise trend. Huang Hefeng reports even more than cervical cancer. Postmenopausal bleeding and cancer does not necessarily proportional to the degree. The amount of bleeding may be small, not more than the number of bleeding lesions and cancer may have been more obvious. It should be carefully done gynaecological examinations to identify the vagina, cervix, uterus, annex whether anomalies exist. Because there may be two or more lesions at the same time, such as the presence of senile vaginitis while endometrial cancer, must not have been found because of a disease while ignoring further examination. In addition to cytology, scraping up subparagraph is indispensable checkups step, because diagnostic curettage of the uterine endometrial cancer diagnosis rate was as high as 95 per cent. Domestic-Weiya, 10 of 448 patients with postmenopausal bleeding consultation scraping endometrium, endometrial cancer accounted for 11.4 per cent (51 cases), Romania Qidong such reports is 8.7%. As reported in the literature ranges from 1.7 to 46.6 per cent, generally below 15%. Second, dysfunctional uterine bleeding menopause usually menstrual disorders, especially bleeding more frequent, regardless of whether it is normal uterine size, we must first do blow up, then clearly the nature of the treatment. Health endometrial carcinoma what will happen in the early growing period and even fertility of women. Shandong Provincial Hospital had mixed endometrial cancer patients, as young as 26 years old, menorrhagia three years, according to the treatment of dysfunctional uterine bleeding invalid, the final diagnosis confirmed to scratch endometrial carcinoma. So young women with irregular bleeding for 2 to 3 months null and void, should also be identified in consultation scratch. Third, endometrial atypical hyperplasia was particularly prevalent in women of childbearing age. Endometrial severe dysplasia in morphology, and it is sometimes difficult to identify well-differentiated adenocarcinoma. Usually not typical endometrial hyperplasia, can be manifested as pathological foci, squash the normal epithelial cell differentiation better, squamous metaplasia or visible fat lotus paste with color, such as non-invasive necrosis performance. And endometrial adenocarcinoma cells nucleus, chromatin more deeply stained, and cell differentiation bad, nuclear fission, the cytoplasm less often occurred infiltration and necrosis. With well-differentiated endometrial adenocarcinoma early identification: ① dysplasia are often the surface of epithelial integrity, and adenocarcinoma is not, as they see a more complete picture of the surface epithelium or squash can be excluded endometrial adenocarcinoma. In addition, endometrial adenocarcinoma often hemorrhagic necrosis; ② different drug therapy response, dysplasia, the effective dose is too small a slower, sustained long, once the withdrawal may soon recurrence; ③ age: young consider dysplasia, challenger to consider the possibility of endometrial adenocarcinoma. 4, submucosal uterine or endometrial polyps osteoma performance menorrhagia or more menstrual extended, or bleeding at the same time be accompanied by vaginal discharge fluid or bloody discharge, clinical manifestations and endometrial cancer are very similar. But through intrauterine exploration, subparagraph curettage, the uterus lipiodol angiography, or hysteroscopy can make differential diagnosis. 5, cervical cancer and endometrial cancer of the same as performance irregular vaginal bleeding and fluid increased. If pathological examination from consideration for squamous cell carcinoma of the cervix. Such as adenocarcinoma were identified its source would be difficult, such as mucus glands can be found, then the hair on the neck of the possibility of more. Japan Okudaira, such as that in invasive cervical adenocarcinoma, carcinoembryonic antigen (CEA), the positive rate is high, therefore, for CEA immunohistochemical staining, with the help of cervical adenocarcinoma of the endometrium identification. 6, primary fallopian tube cancer vaginal discharge fluid, vaginal bleeding and lower abdominal pain, vaginal smears and cancer cells may find similar and endometrial cancer. Fallopian tube cancer and endometrial biopsy negative, and Gongpeng palpable tumors, unlike endometrial carcinoma. If mass palpation not small, can be diagnosed through laparoscopy. 7, the elderly uterine mucositis combined intrauterine wound pus from the vagina frequently manifests itself empyema, or Nongxue of bloody fluid, the uterus increased more than softened. B then check through expansion of the Palais from cancer, inflammatory infiltration organizations only. Empyema regular uterine cancer of the cervix and endometrium cancer or both, must pay attention to differential.