Tuesday, February 26, 2008

Esophageal cancer etiology and risk factors

There are several major factors:
(1) cigarettes and alcoholic drinks: Long-term smoking and alcohol consumption and the incidence of esophageal cancer.
(2) the partial esophageal injury: long-HI into scalding diet may also be carcinogenic factor. Various caused by the original solid prolonged of esophagitis, Esophageal cancer is a possible precursor lesions, in particular with change as cells are greater risk of carcinogenesis. Esophagitis, or in the thoracic esophagus.
(3) nitrosamines: nitrosamine compounds is a very strong carcinogen. The sauerkraut consumption volume is proportional to the incidence of esophageal cancer. Some foods marinated process often fungal contamination. Mold can bring in food and nitrite secondary amine content increased.
(4) the role fungi: Alternaria mycophenolate, such as aflatoxin in food exists in the mold are high-carcinogenic substances.
(5) nutrition and trace elements: a lack of dietary vitamin, protein and essential fatty acids, and other components of a lack of will enable the esophageal mucosa hyperplasia, change as further can cause cancer.
(6) Genetic factors: population and genetic susceptibility and environmental conditions.
(7) Other factors: eating too fast, eating food may cause esophageal mucosal injury, repeated damage can cause mucosal hyperplasia of change, the final lead to cancer.

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