Thursday, February 28, 2008

How diagnosis and treatment of scleroderma local

Partial - is a group of scleroderma skin or strip hard into the characteristics of the disease. It is not accompanied by visceral damage and serological change, Therefore it is not a systemic scleroderma. In some of scleroderma, to see the most hard-spot disease, and several films or film damage, can occur at any site, but abdominal, back to common, followed by the limbs and face and neck. Early lesions are round, oval or irregularly shaped ship edema of the patch, are pale red or purple. after becoming white or atrophic scars. Otherwise, of a pan-hard spot disease, a rare, the number of more damage can be distributed in various body parts, but rarely involved Face; damage to the nature and development of a similar hard spot disease, but lesion area, widely distributed; although no system damage, but patients often fatigue, weakness, emaciation, and the festival pain, neuralgia, abdominal pain, migraine and mental disorders, some patients may develop into systemic scleroderma. Another deep hard spot disease, or generalized hard spot disease of the skin, inflammation and fibrosis mainly in the subcutaneous tissue, surface brown Depression. Dropwise hard spot disease of the skin lesions occurred in good neck and chest, shoulders, back and other places, mung bean to even five minutes coins soybeans, sets clusters or linear arrangement, a pearl or ivory white mother of a little round Depression grouper, smooth surface, a purple-red halo around or pigmentation, changed after shrinking. Its linear hard spot disease or banded linear lesions were named after, it is local-type scleroderma. Major occurred in children and young people. Lesions often intercostal and along the side of a zonal distribution limb, often single, sometimes a few of the damage which might be nearby, is made up of hard plaque or drop scleroderma damage, lesions near the affected joints can be functional contracture . Occurred in the Department of the lesions were vertical distribution, such as the knifed - shaped. Partial-type scleroderma patient's blood, urine routine, erythrocyte sedimentation rate were normal, immunology inspection nor abnormal. Partial the better prognosis of scleroderma patients can be hard to spot after remission after treatment or dissipated, only scar left by shrinking or pigmentation. The hard part of the magic damage scleroderma, adrenal cortex hormones suspension can be used, such as acetic acid triamcinolone acetonide 5-10 grams / liter, or prednisolone (prednisolone) 2.5 g / liter, When the skin is shrinking phenomenon, the need to stop injecting. The lesions can also be injected hyaluronidase daily 150 mg. The linear scleroderma treatment, in addition to using the law, limb and joint contracture in the case, a system of physical therapy, such as audio physiotherapy, wax therapy, and physical exercise. When necessary, to disarm contracture surgery to correct deformities. The pan-onset hard spot disease patients, oral adrenocortical hormones, such as prednisone (prednisone), and other treatment.

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