Metabolic cataract etiology and clinical manifestations

In vivo metabolism of material caused by abnormal metabolic Crystal turbidity called cataract. 1. Diabetic cataract (diabetic cataract) (1) causes According to the study shows that in recent years, Increased blood sugar, glucose content increased crystal, crystal with aldose reductase activity increased, too much glucose into sorbitol. In Crystal sorbitol accumulation, increasing the permeability of pressure, Crystal excessive moisture absorption and swelling, degenerative, and ultimately turbidity. (2) clinical performance of non-insulin-dependent diabetes, cataracts occurred hours earlier than normal man-made, but the symptoms, signs and similar senile cataract. Insulin-dependent diabetes, if poor glycemic control, crystal can be in a few weeks or a few months completely turbid, characterized by the lens capsule under the cortex snow flake at various points, or turbidity. (3) treatment of diabetic control, application aldose reductase inhibitors prevent the accumulation of sorbitol; surgical extraction. 2. Galactose cataract (galactose cataract) with the lack of galactose kinase or galactose - 1 monophosphate UDP transfer enzyme, galactose and in a 1 1 galactose phosphate accumulation in the water and the crystals. Within the crystal into sweet alcohol; sweet alcohol leading to accumulation in the crystal crystal fiber edema and turbidity. The disease is autosomal recessive inheritance.