Neonatal Clinical manifestations of hemolytic disease

The severity depends on the degree of hemolysis, Hemolytic entered fetus depends on the severity of the number of antibodies. Clinical manifestations of this disease so very different. Light to the slow progress, general status of small, fast progress in severe condition, a lethargy, anorexia, bilirubin encephalopathy or even death. (1) edema Massive destruction of red blood cell hemolysis, anemia and cause hypoxia. Hypoxia affect liver protein synthesis and increased capillary wall permeability, and edema of fetuses. Serious edema often stillbirth, ABO hemolytic children with symptoms of this rare. (B) Jaundice Jaundice appeared earlier, progress rapidly, often after birth within 24 hours there. Especially those Rh hemolytic jaundice appeared earlier. Jaundice rapid deepening, 3 to 4 days reached the peak, more than 342 txmol / L (20mg/d1) to combine bilirubin not dominated. (3) anemia RBC damage consistent with the degree of anemia, severe anemia can lead to heart failure and heart expanded. Rh hemolytic disease appeared early and severe anemia, mild anemia, cord blood hemoglobin> 140 g / L, moderate anemia <140>