Systemic sclerosis kidney damage

Systemic sclerosis (systemic sclerosis) is in excess of connective tissue, organs and vascular wall accumulation, The connective tissue abnormality is not the source of clearance. The resulting series of clinical symptoms. Common involving organs: skin, kidney, gastrointestinal tract, lung, heart and large blood vessels. Incidence reasons unclear, as autoimmune diseases. Women common, age of onset of 30 to 50 years old, and HLA-DR3, DR5, C4null and other genes. Renal failure is the main cause of death of the disease. Approximately 40% to 70%.