Saturday, February 23, 2008

Vitiligo clinical manifestations and Classification

TCM called vitiligo white vitiligo, white split, white refuting wind. Vitiligo is a skin pigment loss of acquired diseases, for the performance of local or generalized pigment loss. The incidence rate of about 0.5% to 2%, the rest of the world has occurred. The disease can be involved all race, color generally shallow low incidence of people, the deeper the color higher incidence of people. Occur at any age, chronic after. Lesions limit for the size of the stain from around pigment deepened, the number of uncertainties, border clearly, it can be white hair, without subjective symptoms, the body parts may occur, but to face, neck, back common, and sometimes zoster lesions showed segmental or arranged. White spot disease early when (also known as skin lesions) color junior, are pale white, with disease progression, white gradually deepened, was pure white. Illness develops to a certain extent, hair Cui, and gradually turns white hair, serious, Cui hair and hair loss, sweat glands pore also will be limited due to the summer sweat gland lesions District occlusion without sweat overflow hole. This period of complete loss of melanoma cells, treatment with certain difficulties. Others believe that in the epidermal junction of melanocytes tyrosinase system function loss, will not pay 22% of GABA oxidation hydroxyphenyl alanine (Dopa), resulting in the formation of melanin obstacles. The second category of vitiligo (1) complete leukoplakia: pure white porcelain or white, not white pigment regeneration phenomenon leukoplakia organization melanocytes disappear, and more Palestinian reaction negative. (2) incomplete white: white pigment Center Visibility, leukoplakia organization melanocytes reduced, more positive Palestinian response
Vitiligo-2 (1) Advanced: leukoplakia increased, the original white transitional gradually expand to normal skin, blurred realm. (2) stabilization period: leukoplakia stop development, state clearly that marginal white pigment deepened.

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