Vitiligo to whether and endocrine

Vitiligo is the relationship between endocrine and relatively close. From our statistical analysis of 2060 cases of clinical data, whether they are endocrine factors accounted for 23.6%. Among them, hyperthyroidism, diabetes, menstrual disorder half of women of childbearing age breast hyperplasia or lobular breast fibroids ...
Then endocrine metabolism of the pigment have any effect? Experimental study show that: melanoma cell stimulating hormone, skin-stimulating hormone, the hormone can promote metabolism of melanin synthesis, and corticosteroids, and epinephrine and norepinephrine, thyroxine and melatonin can the metabolism of melanin synthesis inhibition. In order to make patients aware, we briefly explain:
1, melanoma cell stimulating hormone. Studies show that in recent years: human melanoma stimulating hormone may promote skin secretion from the anterior pituitary cells in the secretion. Melanoma cells stimulated with a β - two points, when the patient received a lot melanin stimulating hormone therapy, short-term local happen pigmentation.
2, Paper-stimulating hormone. Paper-stimulating hormone secreted by the anterior pituitary. Clinical use of skin-stimulating hormone after many patients to love disease-like pigmentation, the original Nevus color deepened, and a new Nevus, this may be due to skin-stimulating hormone containing melanin stimulating hormone is why there promoting the use of skin in the treatment of vitiligo reports.
3, sex hormones. Male hormone and sex hormones, including female hormones, the male hormone testosterone is representative of, such as testosterone propionate ketone; female hormones such as progesterone and estrogen. Sex hormones have deepened the role of skin color, such as pregnant women accompanied facial chloasma and nipple, areola and other places, colors deepen, as the female hormone in pregnant women increased overheads. Again patients with liver diseases skin pigmentation, face Chloasma (also called liver spots), which is due to the liver disease in patients with hormone inactivated dysfunction, resulting in the blood caused by increased concentrations of estrogen.
4, corticosteroids. Corticosteroids: prednisone, dexamethasone and Tsing examination of the Song and other secreted by the adrenal cortex, and its role in the metabolism of melanoma and melanoma cells stimulated mainly related. Under normal circumstances, blood melanin stimulating hormone and corticosteroids are relatively balanced, once disorders, affecting color. We have found vitiligo patients taking prednisone for treatment of arthritis after leukoplakia expanded increased. Case analysis from the animal experiments, skin experts speculate: corticosteroids can skin turns white is the main mechanism of inhibiting the secretion of pituitary melanoma cell stimulating hormone, and on the direct role of melanoma cells is minimal.
5, epinephrine and norepinephrine. Epinephrine and norepinephrine from the adrenal medulla secretion of the hormone, which in a quiet state secretion rarely encountered cold, pain, emotional factors make the body in a "state of tension", in the sympathetic nervous excitement at the same time, the adrenal medulla secretion increased, so the two hormones increase. Traces of epinephrine that can inhibit melanoma cells in vitro stimulation on frog skin melanoma cells.
6, thyroxine. Thyroid hormone secreted by the thyroid. Thyroid agents in thyroxine, double iodine thyroxine of the complex inorganic iodide can skin color smeared out, but Frog melanoma cells had no effect. In addition, associated with vitiligo cases of hyperthyroidism is not uncommon, when they individually after resection of thyroid patients with vitiligo change.
7, faded melanoma. Melatonin melanoma mainly by the pineal gland secretion. The pineal gland secretion and Light is closely related to extend the light faded melanoma and can inhibit secretion.