Why should there be breast fiber cystic hyperplasia

Fiber cystic disease of the breast is neither an inflammatory, non-neoplastic diseases, but in fibrous tissue and breast epithelial hyperplasia with cyst formation of a disordered structure of breast disease, the foreign scholars called fiber cystic breast disease. The disease in the 1829 first described by Astley Cooper, and found that the cancer can occur in the latter part, has been considered a precancerous lesions, by the widespread concern of many scholars, for a large number of clinical studies and follow-up observation. Now that the disease first glandular epithelial hyperplasia, emerging fibrous tissue hyperplasia, fiber cystic hyperplasia and adenoma formation of a series of fiber morphology of pathological changes. Disease can be gradually progress can be stopped in a stage to the self-healing, some patients can develop cancer. Because of the different periods of different clinical manifestations, and therefore a wide variety of public life, such as breast hyperplasia, lobular hyperplasia and dysplasia breast. Combined with clinical and pathological findings, named fiber cystic sick more appropriate. This disease for women in breast diseases to see a maximum. In the 30-50 age group in the incidence rate of around 15 percent, in breast disease specialist out-patient clinics in 50 percent to 70 percent. Peak age of 30-45 years old, rarely occur in postmenopausal women. Causes of Endocrine disorder is the main reason for causing this disease, this view has now been widely accepted. Breast is estrogen and progesterone hormones such as prolactin and the target organ. Estrogen can mammary duct ectasia, extending, and promote cell protein synthesis and the use of sugar, and increased capillary permeability within the Organization for the Advancement of water and sodium retention. Progesterone can estrogen that has been the acinar or further developed into lobules, while reducing capillary permeability and organizations within the Shuinazhuliu. Prolactin on mammary epithelial growth and development of the role of promoting the same. When estrogen levels to absolute or relative increase in the level of progesterone or relative or absolute decrease, are back to within a hormone imbalance in the environment, and ultimately caused the irregular structure of the breast. Has been confirmed, luteinizing hormone can promote ovarian follicular maturation and ovulation, followed by stimulation of progesterone and prolactin secretion. Both can promote mammary epithelial and stromal hyperplasia. Some scholars think that oral contraceptives may be induced fiber cystic illness, taking xanthine and other structurally similar drugs, smoking may increase the illness. In short, cystic breast disease of the fiber etiology and pathogenesis is very complicated, estrogen pathogenic role of the more obvious, such as progesterone and the role of prolactin, the researchers need to be further explored and explained.