Tuesday, March 11, 2008

Acute pulmonary abscess

As outlined lung abscess is caused by a variety of pathogens suppurative lung infection, for early lung infection inflammation, then necrosis, liquefaction, a peripheral surrounded formation of granulation tissue abscess. Clinical features : high fever, cough, abscess ruptured after entering the bronchial cough sputum large septic smell. X-ray shows that gas-liquid-containing the cavity. Occur in the prime of their life, more men than women. Since antibiotics widely used, the incidence rate is significantly lower. Pathology and pathogenesis of acute lung abscess infected with the bacteria generally mouth, the upper respiratory tract bacterial always keep in line, including aerobic, facultative anaerobic and anaerobic bacteria. More important is the anaerobic bacteria Streptococcus bacteria streptococcus, nuclear tablets spindle bacteria, and production of melanin rods and bacilli and stomatitis VEILLONELLA; common aerobic and facultative anaerobes for pneumococcal, Staphylococcus aureus, hemolytic streptococcus, Klebsiella pneumoniae and Escherichia coli, Pseudomonas aeruginosa, Proteus, etc.. Clinical manifestations in patients with lung abscess, 70% -90% of the cases of acute onset, and most of a tooth, Oropharyngeal Tienam, or surgery, tiredness, catch cold and other history. Patients with flu chills, high fever, body temperature was 39 -40 ° C, accompanied by a cough, phlegm or mucus cough mucopurulent sputum. Inflammation can cause pleural involvement chest pain and breathing with the. The extent of the lesion, there short breath. Also a lack of energy, malaise, anorexia, and other systemic toxicity symptoms. If not promptly to control infection in the pathogenesis of 10 -14 days, a large number of sudden cough and sputum septic smell of necrotic tissue, up to a daily 300-500ml. Stinking up phlegm system infection caused by anaerobic bacteria. About 1 / 3 of patients with varying degrees of hemoptysis, occasionally, a large number of hemoptysis and suddenly died of suffocation. Generally be expectorated sputum large, the temperature dropped attendant symptoms of systemic toxicity reduction, within a few weeks of the general gradually returning to normal. Some patients slow the disease, a general infection of the respiratory tract symptoms, such as cough, cough and hemoptysis evenly, with high fever, chest pain and so on. An inspection. Laboratory tests : blood : blood leukocytes total (20-30) × 109 / L, Neutrophils 90%. Sputum bacteriology : bacteria in the drug-sensitive test to select effective antibiotics. 2. X-ray inspection : X-ray showed large areas of dense infiltration fuzzy shadow edge unclear, or thick sheet of the league shadow in a distribution or of the whole lung. Or a hollow, fluid-ping. 3. Bronchoscopy : help to identify causes and timely treatment. For the treatment of acute lung abscess principle is antibacterial and sputum drainage. Acute bacterial infection of the lung abscess, including anaerobic bacteria, in general, are sensitive to penicillin, in the course of disease in patients within one month, After aggressive antibiotic treatment, the cure rate of up to 86%. Anaerobic pathogens lung abscess, only Bacteroides fragilis is not sensitive to penicillin, and for Lincomycin. clindamycin and metronidazole-sensitive. Antibiotics such as effective, desirable 8 -12 weeks, until X Buy empty and the inflammation disappeared, or only a small amount of residual fibrosis stability. Medication in the body, on the basis of available antibiotics local drug treatment, As the 300,000 units of penicillin diluted in 5-ml saline, for the first Puluoka by 4%, or 2% of Puluoka by local anesthesia, followed by the nose ring A catheter or infusion of antibiotics membrane to puncture trachea, by abscess appropriate location for a stationary supine posture hours daily. Conditional, via bronchoscopy in X-ray fluoroscopy, will bronchiole catheterization Vomica close to the drainage bronchial lesions. Direct injection of antibiotics Solution. After aggressive medical therapy and can not be closed Vomica chronic lung abscess, and repeated infection or patients with massive hemoptysis, to be considered for surgical resection.

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