Tuesday, March 11, 2008
Cardiac myxoma
Overview of cardiac myxoma is the most common primary cardiac tumor, mostly benign and malignant rare. Myxoma can occur in the heart of all the endocardial surface, 95% occurred in atrium, about 75% located in the left atrium, 20% located in the right atrium, left ventricle and right ventricle to 2.5% each. Left atrial myxoma tumors often occurred in the vicinity of Waterloo Park eggs, due to clinical tumor mitral valve plug, lead to mitral stenosis or regurgitation, mucinous tumors can occur at any age, but the most common in middle age, female styles. Cause pathogenesis myxoma can occur in the heart of all the endocardial surface, 95% occurred in atrium, About 75% located in the left atrium, 20% is located in the right atrium, left ventricle and right ventricle to 2.5% each. Left atrial myxoma tumors often occurred in the vicinity of Waterloo Park eggs, due to clinical tumor mitral valve plug, lead to mitral stenosis or regurgitation, mucinous tumors can occur at any age, but the most common in middle age, female styles. Tumor sizes, and more pedunculated atrial or ventricular wall connected shape diverse, rich, shiny appearance, translucent noticeable. Myxoma can occur in the heart of all the endocardial surface. Clinical manifestations of this disease depends on the clinical manifestations of the tumor location, size, nature and the availability and pedicle length. 25/42 pedicle elderly prone to cause atrioventricular valve stenosis or regurgitation occurred hemodynamic changes, there was a series of symptoms, small tumor pedicle short, the long-term asymptomatic. (1) obstruction symptoms : Early frequent palpitations, shortness of breath, reduced exercise capacity, Left atrial myxoma as obstructive pulmonary vein or mitral valve may have mitral valve disease resembles the symptoms of pulmonary bleeding; paroxysmal nocturnal dyspnea, hemoptysis silk sputum, weight can be computed jugular, hepatomegaly and lower extremity edema. Right atrial myxomas as superior vena cava obstruction, tricuspid mouth with pericardial effusion appeared similar symptoms; Jugular venous engorgement. hepatomegaly and edema. The disease with obstructive symptoms of postural changes in the characteristics of the attack and if there are positions related to the paroxysmal vertigo and breathing difficulties. atrioventricular block tumor suddenly aroused valve stroke volume significantly decreased, fainting or sudden cardiac arrest. (2) embolization : mucinous tumor or tumor surface debris shedding can occur thrombosis, pulmonary embolism cycle. Left atrial myxoma about 40% occurred embolization, right atrial myxoma were rare embolism. (3) systemic symptoms : fever mainly, ESR increase, anemia, weight loss and serum α2, beta globulin abnormal increase, this may be related to tumor necrosis and hemorrhage of inflammatory cell infiltration. An inspection, testing : anemia, block ESR, serum protein electrophoresis and beta α2 globulin increased. 2, ECG : There atrium and ventricle increased, I-II degree atrioventricular block, incomplete right bundle branch block ECG changes. Atrial fibrillation may also have occurred. More severe disease may have ST-T changes. 3, X-ray : Left atrial myxoma are pulmonary bleeding, and pulmonary highlight of the left atrial and ventricular expansion Right atrial myxomas displaying the superior vena cava shadow widened, right atrium and right ventricle to expand. 4, echocardiography : Left atrial myxoma in the left ventricular cavity to see abnormal light reflex points Flake mission activities in the left atrium, Left ventricular between systolic back to the left atrial cavity, the diastolic mitral to enter the left ventricle, mitral anterior leaflet EF reduce the slope, Left atrial enlargement. 5, cardiovascular angiography : selective pulmonary angiography or continuous film radiography, left the room may appear occupying filling defect shadow indirectly confirmed atrium tumor, Right atrial myxomas general for the inferior vena cava or right atrial angiography may also appear right room occupancy filling defect shadow. Treatment of the disease have occurred in danger of sudden death, the right to be suspicious early diagnosed patients, the diagnosis is clear, an early heart surgery can get better results.
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