Tuesday, March 11, 2008

Lung, pleura Amebiasis

Overview of E. histolytica parasite infection caused by lung and pleural suppurative inflammation, liver disease in mice occur in the lower right lung, blood-borne most of both lungs were multiple changes. A diagnosis. History and symptoms : frequent diarrhea or pus is the history of acute fever, fatigue, night sweating, loss of appetite and other symptoms, coughing, Caledonia sputum, chest pain, some patients may have bloody sputum, hemoptysis, or sputum Caledonia chocolate color, such as abscess ruptured into the chest, There was intense chest pain and breathing difficulties even pleural shock. 2. Check body found : the side of the chest lesions decreased respiration, intercostal space may have tenderness, knocking pain, and partial spontaneous delivery was voiced. decreased breath sounds or rales, there should be signs of pleural effusion. Chronic anemia can be thinner and clubbed fingers (toe). 3. Supplementary examination : (1) leukocyte count and classification : the acute phase increased, and secondary infection after more evident. People with chronic diseases leukocyte count and classification can be normal or reduced in a red blood cell, can reduce and increased ESR. (2) sputum, pleural effusion inspection found protozoa Acanthamoeba trophozoites or can be confirmed. (3) serological examination : indirect hemagglutination, the indirect fluorescent antibody ELISA test, convection immunoelectrophoresis have such high sensitivity, negative test results are helpful in removing the disease. (4) the chest X-ray examination : sustained high density large shadow around infiltration can be hazy. Abscess formation after shadow, there will be peaceful solution and see irregular abscess wall. Acanthamoeba pleural disease, it was manifested as pleural effusion, pyopneumothorax or pleural thickening, adhesion, and other features. (5) Ultrasonic Inspection : contribute to the diagnosis and determine the location of thoracic fluid and fluid volume. 4. Differential diagnosis : the disease to lung abscess in bacterial pneumonia tuberculosis and other types of empyema differential phase. A treatment. Acute patients should rest in bed, heating is required rehydration give expectorant COAN objects, available when necessary trypsin and saline aerosol inhalation Like a diluted sputum that can be used when severe chest pain analgesics. 2. Drug therapy : metronidazole (metronidazole) 0.4 - 0.8 g, 3 times / d uniforms, 5 ~ 10 days for a course of treatment, if necessary, can be reused. Severe should intravenous administration; The first 15 mg / kg after 7 .5mg/kg once every six hours, 5% dissolved in 250 ml of intravenous glucose infusion, 7 ~ 10 days of treatment. Ante can choose amide (Entamidum) 0.5g, 3 times / d clothes, a course of 10 days. Metronidazote imidazole p 2 g, 1 / d service, a course of 3 days. 3. Pleural effusion or empyema : puncture fluid (pus) or must-drainage and drainage must be made. also available metronidazole 0.5 g intrapleural injection of local treatment. 4. Other therapy : pulmonary abscess sputum volume should shun spaces drainage expectoration. Bacterial infection with antibiotics to be added. Any of the following circumstances (1) medical treatment and void; (2) chronic fibrosis; (3) formation of bronchopleural fistula, Surgical treatment available.

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