Tuesday, March 11, 2008
Staphylococcus aureus pneumonia
Overview of Staphylococcus aureus pneumonia called Staphylococcus pneumonia, adult pneumonia accounted for 2 ~ 3%, child care, the frail elderly and the latter surgical morbidity; higher clinical divided into primary and secondary categories. Etiology and Pathogenesis a pathology, primary : Frequently Asked to influenza, measles and antibiotic selection process, fever, cough, pus cough sputum, chest pain as the main symptoms, lung Visibility single or multiple lesions abscess. 2, secondary : also known as blood-borne, the incidence of slower clinical to high fever, chills, breathing difficulties and other symptoms of sepsis for the outstanding performance of a severe right consciousness obstacles, respiratory failure and shock; multiple small pulmonary abscess, skin and other parts of primary pyogenic lesions can be seen. Clinical manifestations of staphylococcal pneumonia despite ferocious. But some condition is not serious. Individual course of a relatively slow. Sometimes chronic pneumonia or chronic lung abscess. Clinical symptoms and pneumococcal pneumonia symptoms similar. Staphylococcal pneumonia is characterized by repeated easily lead to shiver. Necrosis with abscess formation and pulmonary cysts (most of which are found in infants); Emergency conditions and failure is obvious. Empyema more common. Staphylococcus aureus found primarily in the thoracic incision of the chest wall empyema, or post-traumatic hemothorax use of the drainage empyema China. A diagnosis, the patient was found to be expectorated sputum Staphylococcus aureus can be suspected of the disease, diagnosed from blood culture, Empyema Pott or tracheal or chest extracts were found Staphylococcus aureus. Staphylococcus aureus and pneumococcal different, more training, Hence false negative rare. The most common X-ray abnormalities of bronchial pneumonia with or without abscess formation or pleural effusion; lobar consolidation rare. Pneumatoceles strongly suggests to staphylococcal infection. embolic Staphylococcus pneumonia is characterized in adjacent to the site of a multiple infiltration, infiltration becomes empty, these phenomena from vascular causes (such as the right endocarditis or septic thrombosis phlebitis). 2. X-ray examination : Primary pulmonary Visibility fuzzy or dense shadow areas are translucent. Secondary performance of both lungs scattered nodular shadows and various empty. 3, laboratory tests : white blood cell count increased significantly to 20 ~ 50 × 10 / L, and poisoning particles. Sputum culture can be found Staphylococcus aureus. A treatment and strengthen support therapy, the primary Tienam cleared as soon as possible. 2, antibiotics treatment : early, the joint, long course of treatment, use of penicillin G or vancomycin; right-resistant Staphylococcus aureus Isolates of choice Oxacilline, cephalosporins, or with a new generation quinolone antibiotic combination. Antibacterial drugs at least four weeks. 3, the majority of Staphylococcus aureus produce penicillin enzyme, and resistant to methicillin resistance is on the increase. Generally advocate the use of a penicillin-resistant enzyme penicillin (such as oxacillin or naphthalene Fuxilin 2 g, intravenous injection, Each 4 ~ 6 hours a time. Another major drug is cephalosporins : commonly used for cefalotin or cephalosporins Meng more 2g, intravenous injection every four-six hours a meeting, cefazolin 0. 5 ~ 1. 0g, intravenous, each an eight-hour meeting. or 750 mg of cefuroxime, intravenous, Each six-eight hours a meeting. the third generation cephalosporins result is not as good as the first-generation or second-generation agents. Lincomycin Hydrochloride 600mg intravenous injection every six-eight hours on a pair of 90% - 95% effective strains. 4, it is generally believed that, to methicillin-resistant strains of all beta-lactam antibiotics are resistant. In many hospitals, Such strains accounted for hospital-acquired Staphylococcus aureus in 30% ~ 40%. and the only community-acquired infection of 5%. If in doubt or in vitro tests proved to methicillin-resistant, General use of vancomycin. usual dose of 1 g intravenously every 12 hours; have renal failure appropriate dosage adjustments. Prognosis general CFR 30% ~ 40%. resulting in death is due in part the majority of patients with severe complications. However, some adults have very healthy. But after the crises of influenza pneumonia. Disease the rapid development situation. eventually lead to death. Effect of antibiotic slow. long convalescence.
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