Understanding of the pathogenesis of esophageal cancer

Bad eating habits: Food and rough, quality hardware and eating overheating, excessive drinking, and so on, are concerned with the incidence of esophageal cancer.
Other esophageal lesions: Some esophageal lesions, such as esophageal achalasia, esophagitis, benign esophageal stenosis, esophageal mucosa, such as leukoplakia patients with esophageal disease
, The higher the incidence of esophageal cancer, and esophageal mucosa lesions may suffer long-term stimuli.
Nitrite Derivatives Impact: This is a highly carcinogenic substances, esophageal high incidence area residents like to mouldy food such as sauerkraut, dried turnip,
Miso, cornmeal, etc., containing nitrite and its predecessor, the more material (nitrate, nitrite), the role of nitrate can be fungal or by the acid in the stomach for
Use can be reduced to nitrite. Streptomyces Decomposable food protein content increased 2 amine, and promote Synthesis of nitrite. Trace Elements: According to epidemiological survey found that esophageal cancer in the high incidence area of water and soil molybdenum, copper, cobalt, manganese, iron, nickel, zinc, and other trace elements in the low may
And the incidence of esophageal cancer. Mo, nitrate accumulation in plants, and under certain conditions will promote the formation of nitrite amine carcinogens.
Genetic factors: high incidence area of esophageal cancer in patients with positive family history, there are up to 27% ~ 61% of patients with familial chromosomal aberrations in peripheral lymphocytes higher rate. This shows that
, Genetic factors in the pathogenesis of esophageal cancer in a certain relationship between internal and external factors may also is a common role.