Chlamydia pneumonia diagnosis

1. Chlamydia trachomatis pneumonia in 1975 was the beginning of neonatal chlamydia pneumonia, secondary to his card after Nongxing inclusion. The disease infected more from the mother of eye infection can be transmitted through nasal duct into respiratory tract. Symptoms after birth more than 2 to 12 weeks there, the slow onset, first performance of the upper respiratory tract infection, fever or no more than occasional low heat, and then a cough and shortness of breath, often a small suction-or wet La twist pronunciation, rare Breath and wheezing. Chest film shows extensive bilateral and interstitial pulmonary infiltration, over-inflated levy more common, it is occasionally the leaves change. Peripheral blood white blood cell count normal, eosinophilia. Throat swab from the nose must Guaqu to epithelial cells. Also available direct fluorescent antibody test (DFA), enzyme immunoassay test (EIA) detection of Chlamydia trachomatis antigen nasopharyngeal specimens. Serological examination of specific antibody diagnostic criteria for the double-serum antibody titers more than four times higher, or IgM> 1:32, IgG> 1:512. PCR technique can also be applied directly detect chlamydia DNA. 2. Chlamydia psittaci pneumonia or from contact with infected poultry in bird droppings, poultry raising, slaughter and sale of the occupational disease. The rare human infection. Pathogens from the secretions and excreta, the carrier can be a long time. Chlamydia psittaci enter the body through the respiratory tract, in single cells within the breeding and release toxins, disseminated by the blood flow to the lungs and body tissue, blood vessels and cause lung sound around the cell infiltration, hilar lymph nodes. The incubation period 6 ~ 14 d, the incidence was a cold-like symptoms, often 38 ~ 40.5 ℃ of fever, cough early for dry cough, after a sputum, difficulty breathing or light or heavy. The relative ease with veins, muscle-ache, chest pain, loss of appetite, occasional nausea and vomiting. Such as systemic infection, a central nervous system symptoms of infection or myocarditis performance, occasionally jaundice. Many liver, splenomegaly, and the need to typhoid fever, sepsis identification. Chest X-ray examination, from the periphery to the hilar, especially lung field down that middle ground glass-like shadow of a shadow-like. Peripheral blood WBC normal, ESR increase in the prevalence of early slightly faster. Pulmonary effusion swallowed up by the cells to be investigated see inclusion of chlamydia. Children with mild fever 3 ~ 7 d gradually retreat. In of 8 ~ ~ 14 d, severe 20 ~ 25 d cooling. After the weakened immune disease, relapse, it is reported relapse rate of 21 percent, then the infection rate of around 10 percent. 3. Chlamydia pneumoniae pneumonia clinical manifestations of this non-specific, and mycoplasma pneumonia楥similar. Onset ease, long course, the general symptoms of light, accompanied pharynx, laryngitis, and sinusitis characterized. Upper respiratory tract infection symptoms dissipated after a wet and dry La-such as bronchitis and pneumonia. Sustainable cough symptoms more than three weeks. Normal white blood cell count, chest film non-specific, multi-leaf for the unilateral invasion, expressed as segmental pneumonia, severe bilateral pneumonia was extensive. Chlamydia trachomatis pathogen inspection and pneumonia, from the lessons of nasopharyngeal airway or so cell culture, chlamydia pneumoniae positive. Or fluorescent light of Chlamydia pneumoniae specific monoclonal antibodies in the cell culture to identify the Chlamydia pneumoniae. Chlamydia pneumoniae DNA PCR test is more sensitive than culture, but with throat swab samples testing might not ideal, as serological testing Chlamydia pneumoniae specific antibody. Trace immunofluorescence (MIF) test for detection of Chlamydia pneumoniae is the most sensitive. IgM in ≥ 1:16 or IgM antibody titers ≥ 1:512 or more than four times higher, diagnostic value.