Hemorrhagic newborns and late-life K deficiency.

Hemorrhagic newborn is a result of vitamin K-dependent clotting factor physiological attributable to the decline in the self-limited disease, the normal full-term infants after birth in more than two to five days disease, premature infants can be extended to two to three weeks disease, bleeding site多见to digestive tract. Hemorrhagic neonatal morbidity due to the lack of neonatal vitamin K, so that clotting factor Ⅱ, Ⅶ, Ⅸ, Ⅹ (the clotting factor necessary for the synthesis of vitamin K participation, also known as vitamin K-dependent factor) in less than a full liver , Thus leading to bleeding. Cause of neonatal vitamin K deficiency of the reasons: ⑴ from normal food in addition to direct access to vitamin K, the intestinal bacteria can be part of, but the newborn at the time of birth, no intestinal bacteria, so little synthesis of vitamin K; ⑵ vitamin K And rely on the absorption of bile, but especially the newborn premature infants bile acid in low and affected the absorption of vitamin K; ⑶ Chinai newborn infants less than in breast milk and low content of vitamin K (vitamin K content in breast milk for 15 μ g / L, milk for 60 μ g / L). Hemorrhagic newborns for the majority of cases of gastrointestinal bleeding, or performance to vomit blood samples of coffee, black or Taibiandaixue it, followed by skin, umbilical hemorrhage. It is worth noting that, where the regular hospital births are generally routine preventive injection of vitamin K, so in fact the incidence of this disease is not very high, for the main measures is also injection of vitamin K. Late vitamin K deficiency more common in birth after 1 to 2 months of exclusive breastfeeding of infants, exclusive breastfeeding to vitamin K intake is insufficient main reason for the incidence and impact of diarrhea vitamin K absorption and use of antibiotics, sulfa drugs inhibit Gastrointestinal normal flora, a decrease of vitamin K in the gut of the incentives is often. Late vitamin K deficiency Changbiaoxianwei acute cerebral hemorrhage, children looking pale and irritable crying, convulsions, consciousness unclear, dangerous conditions, poor prognosis. So some people advocate of March within the breast-feeding babies, especially diarrhea or frequent use of antibiotics to a monthly injection of vitamin K, to prevent the onset of the disease.