The pathophysiological neonatal asphyxia

Constant newborn monkeys for acute hypoxic experiments, observe the pathophysiology of change and human performance similar to newborns. The first stage Ⅰ (over-breathing period): hypoxia early respiratory activities to strengthen, deepen speed up breathing, heart rate increased slightly faster, blood pressure increase with mild respiratory acidosis, blood pH> 7.25, continuing a ~ 2 minutes. No. Ⅱ (primary apnea period): apnea, to stimulate a response, heart rate, muscle tension is still good, a metabolic acidosis, blood pH 7.25 ~ 7.0. Although at this time respiratory suppression, but can be overcome, sustained about 1 to 2 minutes. The first stage Ⅲ (breathing period): deep breathing without rules, heart rate, acid poisoning, blood pH 7.20 ~ 7.0, peripheral vascular contraction, lower blood pressure, myocardial ischemia, pale skin, muscle tension increased, sustained five to six minutes . The first stage Ⅳ (2nd apnea): cessation of breathing, heart rate decreased, 60 / min, blood pressure dropped, pale skin, muscle tension low blood pH <7.0,>