Friday, August 15, 2008
What is the renal interstitial nephritis? How is it diagnosed?
Tubular an interstitial nephritis is a large group from various causes of kidney disease. Major violations of renal disease and renal interstitial; clinical renal dysfunction to its outstanding performance. On the course, a tubular interstitial nephritis acute and chronic can be divided into two categories; are the cause of infection, drugs, immune-mediated genetic and metabolic obstacles caused by interstitial nephritis, and so on. To clinical medicine who was the most common cause, followed by urinary tract obstruction with the complexity of those arising from chronic pyelonephritis. The main diagnosis is based on: (1) patient medication history or have a history of chronic renal benefits nephritis. (2) early in the disease, the general did not field the ball the clinical features of disease, such as Shuinazhuliu, edema, hypertension, and so on, and renal dysfunction occurred in the early and glomerular dysfunction and disproportionate. In addition, there are renal dysfunction but no high blood pressure, and a mild proteinuria, B2-microglobulin in urine increase. Given a tubular more than 90 percent of the cause of interstitial nephritis may rule, early diagnosis is crucial, even for renal dysfunction have occurred in patients if they can find a good and timely processing of reversible factors (such as urinary obstruction , Infection, etc.), can also suspend its development and even improve kidney function.
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