Saturday, April 9, 2016

How to care for epidemic keratoconjunctivitis?

(A) treatment
The disease is self-limiting disease, which in the course of the process, with the establishment of the immune system, can heal quickly. Therefore, the focus of treatment is to relieve symptoms and prevent the occurrence of corneal and incidence.
1. There is no specific antiviral drugs for adenovirus. Commonly used drugs are:
(1) morpholine quack (ABOB): a 10% to 15% solution and ointment 4 to 10 times / d drops. If necessary, with oral treatment. Adult 1.2 ~ 1.5g / d, children 0.8g / d, orally 3 times. ABOB generally no special effects, a high concentration of the solution drops used too many times, it can occur multiple epithelial erosion.
(2) idoxuridine (IDU): 0.1% IDU solution or 0.25% ointment, 4-8 times / d eye.
(3) 1.25% povidone (PVP) solution or 0.5% ointment, 4-8 times / d eye.
More antiviral treatment is still not sure, we can not shorten the duration of conjunctivitis, can not reduce or prevent the occurrence of subcutaneous infiltration.
2. Antibiotics topical antibiotic eye drops of the disease without treatment, mainly to prevent mixed bacterial infection, commonly used drugs gentamicin, kanamycin solution or ointment, should try to do a suspension, to reduce local irritation.
3. vasoconstrictor drugs can be severe congestive 0.1% adrenaline (epinephrine) diluted 20-fold with saline eye drops, eye congestion can alleviate the symptoms improved. Generally are not too long, with 3 to 5 times / d drops for 1 week for the degree.
4. glucocorticoid
(1) Conjunctivitis: Conjunctivitis in the period, such as patients with severe conjunctival reactions accompanied by pseudomembrane formation, or early symblepharon topical application can reduce symptoms, and prevent or reduce the incidence of corneal lesions. Commonly used drugs are 0.1% fluorometholone (FML) and 0.02% dexamethasone solution, 4 to 6 times / d drops at night with cortisone eye ointment once generally continued to use two weeks for the degree.
(2) keratitis: 2 weeks after symptoms subside when conjunctivitis, keratitis occur without should immediately stop using. If the subcutaneous infiltration should continue to use, mild person (more than 10 infiltrates) may be 0.05% or 0.02% Flumetholon dexamethasone 4 to 6 times / d drops; heavier (10 infiltration stove above) 0.1% available Flumetholon or 0.05% to 0.1% dexamethasone 6-8 times / d drops, if necessary, combined with injection of dexamethasone 2mg, 1 times a day or every other day; a rapid decline until infiltrate or significantly improved, and then gradually reduce the number of drops or eye drops to reduce the concentration of the solution maintenance therapy, do not immediately stop, to prevent recurrence. For the pupil region has little effect on vision or the subcutaneous infiltration, it is best not to use the topical treatment of glucocorticoid.
5. Other drugs in order to protect the cornea, reducing turbidity and complications may be preservative-free artificial tears, glutathione or 1% sodium chondroitin sulfate eye drops; oral vitamin B2, B6, indomethacin or insurance phenylbutazone. Epithelial erosion by more extensive, as far as possible irritation lighter eye drops and eye ointment. If the use of growth factors (EGF, bFGF) or their own serum eye drops, we will achieve better results.
(B) the prognosis
Timely treatment, the prognosis is good.

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